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Hideo Ishitsuka Selected Research

2',3'- O- diacetyl- 5'- deoxy- 5- vinylcytidine

9/2003Augmentation of the antitumor activity of capecitabine by a tumor selective dihydropyrimidine dehydrogenase inhibitor, RO0094889.
3/2003Design and synthesis of the tumor-activated prodrug of dihydropyrimidine dehydrogenase (DPD) inhibitor, RO0094889 for combination therapy with capecitabine.

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Hideo Ishitsuka Research Topics

Disease

8Neoplasms (Cancer)
07/2009 - 03/2003
6Hepatocellular Carcinoma (Hepatoma)
01/2011 - 03/2003
1Inflammation (Inflammations)
10/2008
1Infections
02/2005
1Colorectal Neoplasms (Colorectal Cancer)
09/2003

Drug/Important Bio-Agent (IBA)

2Proteins (Proteins, Gene)FDA Link
01/2011 - 11/2006
2Cell-Free Nucleic AcidsIBA
10/2008 - 11/2006
2DNA (Deoxyribonucleic Acid)IBA
10/2008 - 04/2007
2ProdrugsIBA
04/2007 - 03/2003
2OligonucleotidesIBA
02/2005 - 03/2003
22',3'- O- diacetyl- 5'- deoxy- 5- vinylcytidineIBA
09/2003 - 03/2003
2Fluorouracil (Carac)FDA LinkGeneric
09/2003 - 03/2003
2Capecitabine (Xeloda)FDA Link
09/2003 - 03/2003
25-vinyluracilIBA
09/2003 - 03/2003
2Dihydrouracil Dehydrogenase (NADP) (Dihydropyrimidine Dehydrogenase)IBA
09/2003 - 03/2003
1Cyclin D2IBA
04/2010
1Peptides (Polypeptides)IBA
07/2009
1Biomarkers (Surrogate Marker)IBA
07/2009
1hydrogen sulfite (bisulfite)IBA
11/2008
1CytokinesIBA
10/2008
1dipeptidaseIBA
04/2007
12'-deoxy-2'-methylenecytidineIBA
04/2007
1Pharmaceutical PreparationsIBA
04/2007
1DipeptidesIBA
04/2007
1acarboxyprothrombin (PIVKA)IBA
11/2006
1alpha-Fetoproteins (alpha-Fetoprotein)IBA
11/2006
1Vitamin KFDA Link
11/2006
1Glutathione S-Transferase piIBA
11/2006
1Complementary DNA (cDNA)IBA
09/2003
1eniluracilIBA
09/2003
1Messenger RNA (mRNA)IBA
03/2003
1EnzymesIBA
03/2003
1Thymidine PhosphorylaseIBA
03/2003
1EsterasesIBA
03/2003
1Cytidine DeaminaseIBA
03/2003

Therapy/Procedure

1Therapeutics
03/2003